ADVERTISEMENT

Proprietary COVID-19 and Vaccine thread

Stolen from another board. Thoughts? It has not been peer-reviewed.


Or if you just want a blurb of the abstract

Results: SARS-CoV-2-naive vaccinees had a 13.06-fold (95% CI, 8.08 to 21.11) increased risk for breakthrough infection with the Delta variant compared to those previously infected, when the first event (infection or vaccination) occurred during January and February of 2021. The increased risk was significant (P<0.001) for symptomatic disease as well. When allowing the infection to occur at any time before vaccination (from March 2020 to February 2021), evidence of waning natural immunity was demonstrated, though SARS-CoV-2 naive vaccinees had a 5.96-fold (95% CI, 4.85 to 7.33) increased risk for breakthrough infection and a 7.13-fold (95% CI, 5.51 to 9.21) increased risk for symptomatic disease. SARS-CoV-2-naive vaccinees were also at a greater risk for COVID-19-related-hospitalizations compared to those that were previously infected. Conclusions: This study demonstrated that natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity. Individuals who were both previously infected with SARS-CoV-2 and given a single dose of the vaccine gained additional protection against the Delta variant.
 
  • Like
Reactions: SORT14
Hard to imagine natural immunity being less durable than vaccination. This doesn't really impact the issue, if you feel like you need the vax get it, if you don't don't, but either way take care of yourselves or all of this is one giant virtue signaling fest, like almost everything else is now.
 
I'm obviously concerned about Covid enough to take the shot, but I'm a little confused by your phrasing.

Isn't the Sars Cov-2 virus a spike protein in and of itself? It doesn't cause production like the vaccines?

As far as any conjecture about what messing with RNA does to your immune system, that's fringe stuff but I still don't know if it's been answered fully yet. We do know RNA plays a role in how you fight certain disease, I'm just not sure we know what the use of mRNA to "trick" it does long term. You might be right, maybe it's harmless.

I think the medical community is still learning about the effects of your body producing so much spike protein - I read each does of Moderna can result in up to 40T spike proteins. Is there a limit to what the body can dispose of? Do we know what repeated pumping of spike protein does long term? Either way I hope you're right...I already think these vaccines are a medical miracle, I just don't know if there's a surprise lying in the weeds.


SARS-COV-2 is a virus that's coated with numerous spike proteins, and it has its own RNA on the inside. The way it replicates in your body is this:

1) Use spike proteins to bind ACE2 receptors, which allows them to enter your cells. You have a lot of ACE2 receptors in your lungs, hence all the disease is happening there.

2) Once inside your cells, the virus releases its RNA, and uses your own cells' mechanics to first multiply its RNA.

3) Next, the RNA is used as a template to make the proteins (e.g. spike proteins, among others) to make new viruses.

mRNA vaccines use the same process as step 3 (it's also possible to use step 2 as well, I believe). mRNA vaccines enter your cells, and also use your own cells' mechanics to make proteins. In the case of mRNA vaccines, it only contains enough genetic information to make one type of protein, the spike protein, instead of the whole virus.

You can basically consider mRNA vaccines as "COVID-lite", where it only makes spike proteins instead of whole viruses.
 
I’ve come around and I’m getting the shot, but it’s scary AF. I maybe slept two hours last night. I don’t want the treatment - it’s overwhelming evidence to you guys because you see all of the worst outcomes. You don’t even hear about the thousands (more?) who lose smell and feel a little funky and never even get tested. Even delta is mild for a vast, vast majority of people.

And I’m not saying the vaccines are ineffective at preventing bad outcomes, I’m worried that the same thing that’s tainting research and public perception of IVM is happening with the vaccines - this is an emergency situation and all we are focused on is the short term…and looking for good news.

I wouldn’t even consider it if the delta surge wasn’t starting here and I didn’t have two kids in school…wearing fairly worthless masks in a crowded place, and I didn’t coach HS sports.

But at least in my area you have two choices - get vaccinated and get Covid or don’t get vaccinated and get it. I just hope the treatment doesn’t turn out to be as bad as the disease long term.

Man, we are in almost the exact same place on this.

Short-term vs long-term and benefits vs potential unknown costs will absolutely keep you up at night.

And I'm married with a family. I'm not simply making this choice for myself. It's heavy.
 
  • Like
Reactions: SORT14 and jfegaly
Stolen from another board. Thoughts? It has not been peer-reviewed.


Or if you just want a blurb of the abstract

Results: SARS-CoV-2-naive vaccinees had a 13.06-fold (95% CI, 8.08 to 21.11) increased risk for breakthrough infection with the Delta variant compared to those previously infected, when the first event (infection or vaccination) occurred during January and February of 2021. The increased risk was significant (P<0.001) for symptomatic disease as well. When allowing the infection to occur at any time before vaccination (from March 2020 to February 2021), evidence of waning natural immunity was demonstrated, though SARS-CoV-2 naive vaccinees had a 5.96-fold (95% CI, 4.85 to 7.33) increased risk for breakthrough infection and a 7.13-fold (95% CI, 5.51 to 9.21) increased risk for symptomatic disease. SARS-CoV-2-naive vaccinees were also at a greater risk for COVID-19-related-hospitalizations compared to those that were previously infected. Conclusions: This study demonstrated that natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity. Individuals who were both previously infected with SARS-CoV-2 and given a single dose of the vaccine gained additional protection against the Delta variant.

Just read through that, very interesting findings! It seems to be a pretty well designed study that shows a much, MUCH higher protection for natural immunity vs. vaccinations. The study duration is fairly short, but I see no reason why the results wouldn't hold up over the long term. If anything, I suspect the difference will grow larger.
 
  • Like
Reactions: BamaFan1137
Yea while I’m not looking forward to the flu like symptoms I’m going to have, short term isn’t my concern with the vaccines.

Where do the trillions of spike proteins end up? Have we really closed the book on ADE? Does mRNA have any effects on your body’s ability to fight cancer, Parkinson’s, etc longer term? Why do we have 30 years of research and trials and zero approved mRNA treatments until we faced this Chinese bioweapon?

I don’t think I’m going to experience anything but feeling like total ass butt tomorrow, which I can handle. It’s down the road, the endless boosters, etc that concern me more.

I'm scheduled for Moderna on the 31st.

Be honest, I can trust you I think...if you grow an extra penis, let me know.


...so I can try to get my appointment moved up to the 27th.
 
Oh my


BOMBSHELL UK data destroys entire premise for vaccine push​



This is an absolute game-changer.

The UK government just reported the following data, tucked away in their report on variants of concern:

Less than a third of delta variant deaths are in the unvaccinated.

Let me say that another way - two-thirds of Delta deaths in the UK are in the jabbed.

To be specific:

From the 1st of February to the 2nd of August, the UK recorded 742 Delta deaths (yes, the dreaded Delta has not taken that much life).

Out of the 742 deaths, 402 were fully vaccinated. 79 had received one shot. Only 253 were unvaccinated.

The report is here.

But this is the crucial page. Look at the bottom line.

That data is not very useful without knowing what percentage of which group of the population is vaccinated. Efficacy can only be calculated knowing that information, because the demographics of the vaccinated and the unvaccinated need to be comparable in order to compare the efficacy.
 
Just read through that, very interesting findings! It seems to be a pretty well designed study that shows a much, MUCH higher protection for natural immunity vs. vaccinations. The study duration is fairly short, but I see no reason why the results wouldn't hold up over the long term. If anything, I suspect the difference will grow larger.

I was hopeful when I read it. Then I worried that I was hopeful because it was what I wanted to hear.

Thanks for your input.
 
I'm scheduled for Moderna on the 31st.

Be honest, I can trust you I think...if you grow an extra penis, let me know.


...so I can try to get my appointment moved up to the 27th.
I mean, if I grow another one the same size as the one I have I’m not sure the world gains much. But I will let you know.

I ride J&J or die by the way. Or maybe both. If I stop posting you’ll know. Zero chance my wife logs onto this shithole to tell you guys (and @goldmom ).
 
SARS-COV-2 is a virus that's coated with numerous spike proteins, and it has its own RNA on the inside. The way it replicates in your body is this:

1) Use spike proteins to bind ACE2 receptors, which allows them to enter your cells. You have a lot of ACE2 receptors in your lungs, hence all the disease is happening there.

2) Once inside your cells, the virus releases its RNA, and uses your own cells' mechanics to first multiply its RNA.

3) Next, the RNA is used as a template to make the proteins (e.g. spike proteins, among others) to make new viruses.

mRNA vaccines use the same process as step 3 (it's also possible to use step 2 as well, I believe). mRNA vaccines enter your cells, and also use your own cells' mechanics to make proteins. In the case of mRNA vaccines, it only contains enough genetic information to make one type of protein, the spike protein, instead of the whole virus.

You can basically consider mRNA vaccines as "COVID-lite", where it only makes spike proteins instead of whole viruses.
Great description.

Somthe J&J does the same thing with a specially coded impotent adenovirus?
 
  • Like
Reactions: BamaFan1137
I mean, if I grow another one the same size as the one I have I’m not sure the world gains much. But I will let you know.

I ride J&J or die by the way. Or maybe both. If I stop posting you’ll know. Zero chance my wife logs onto this shithole to tell you guys (and @goldmom ).


There’s a reason it’s Johnson & Johnson 😉

Might want to move that appointment up and switch vaccines @BamaFan1137
 
I mean, if I grow another one the same size as the one I have I’m not sure the world gains much. But I will let you know.

I ride J&J or die by the way. Or maybe both. If I stop posting you’ll know. Zero chance my wife logs onto this shithole to tell you guys (and @goldmom ).

It doubled in size? Wow....what am I going to do with 4 inches??? 😂

I absolutely understand your choice on J&J. I just decided that if I'm in for a penny, I'm in for a pound. And in my anecdotal experience, those around me who have had both vaccines, there were fewer issues with Moderna.

Like yours, my wife won't be on here to issue any farewells. She thinks we're all dumb AF.
 
  • Haha
Reactions: fatman76
Stolen from another board. Thoughts? It has not been peer-reviewed.


Or if you just want a blurb of the abstract

Results: SARS-CoV-2-naive vaccinees had a 13.06-fold (95% CI, 8.08 to 21.11) increased risk for breakthrough infection with the Delta variant compared to those previously infected, when the first event (infection or vaccination) occurred during January and February of 2021. The increased risk was significant (P<0.001) for symptomatic disease as well. When allowing the infection to occur at any time before vaccination (from March 2020 to February 2021), evidence of waning natural immunity was demonstrated, though SARS-CoV-2 naive vaccinees had a 5.96-fold (95% CI, 4.85 to 7.33) increased risk for breakthrough infection and a 7.13-fold (95% CI, 5.51 to 9.21) increased risk for symptomatic disease. SARS-CoV-2-naive vaccinees were also at a greater risk for COVID-19-related-hospitalizations compared to those that were previously infected. Conclusions: This study demonstrated that natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity. Individuals who were both previously infected with SARS-CoV-2 and given a single dose of the vaccine gained additional protection against the Delta variant.
Thanks for sharing. Though it hasn’t been peer-reviewed yet, but I don’t think that’s a reason to dismiss the findings. Interesting to me was that people with prior infection and a single post-infection shot (Pfizer) had the best outcome. I’ll add to this post a couple of other observations when I’m not trying n my phone.

Thoughts on the methods: Logistic regression is a fine choice for classification problems (situations in which the outcome is categorical). In this study, there were essentially 3 categories: Not vaccinated, fully vaccinated, and, well, both (kinda).
Typically, with such large sample sizes I have found random forest to be more robust than logistic regression, but this is no guarantee. From a data science perspective, my method would have been to split the data into two groups, a training set and a test set, with the training set consisting of 80% of the data set. I would have run several different statistical models on the training set (logistic regression, random forest, k-clustering, etc.) and picked the one that performed best on the training data. Essentially I would be overfitting the model intentionally. And then I would run that model on the test set, which would be the remaining 20% of the data that had not been included in the building of the model. Then the results for both sets would be compared. The results would indicate how predictive and valid the findings of the model are. This is essentially the method I use for almost all of my research.
Again, none of this is criticism of the study, just my view. With such a large sample, robust methods are needed, as there could be many things influencing the findings.
Edited to add an interesting article on how vaccination and herd immunity are likely to work best together:

 
Last edited:
  • Like
Reactions: BamaFan1137
SARS-COV-2 is a virus that's coated with numerous spike proteins, and it has its own RNA on the inside. The way it replicates in your body is this:

1) Use spike proteins to bind ACE2 receptors, which allows them to enter your cells. You have a lot of ACE2 receptors in your lungs, hence all the disease is happening there.

2) Once inside your cells, the virus releases its RNA, and uses your own cells' mechanics to first multiply its RNA.

3) Next, the RNA is used as a template to make the proteins (e.g. spike proteins, among others) to make new viruses.

mRNA vaccines use the same process as step 3 (it's also possible to use step 2 as well, I believe). mRNA vaccines enter your cells, and also use your own cells' mechanics to make proteins. In the case of mRNA vaccines, it only contains enough genetic information to make one type of protein, the spike protein, instead of the whole virus.

You can basically consider mRNA vaccines as "COVID-lite", where it only makes spike proteins instead of whole viruses.
Good explanation. And yes mRNA vaccine can use mechanism 2 as well as 3.
 

Were the Pfizer ‘Vaccines’ Approved Because They Establish a Perpetual Need for Booster Shots?​

https://freedomfirstnetwork.com/202...petual-need-for-booster-shots?utm_source=econ
🤣🤣🤣

Let’s extend this further. How about the drug companies invented the virus so they could then finally use the messenger RNA vaccine that they have had in development for 30 years to make trillions of dollars. I mean the vaccine was ready in an awfully big hurry.
Hey @Gator Fever can you pass me some tinfoil? I’m pretty sure @BlueEyedGator17 Left a pretty large supply behind when he was banned for six months.
 
Stolen from another board. Thoughts? It has not been peer-reviewed.


Or if you just want a blurb of the abstract

Results: SARS-CoV-2-naive vaccinees had a 13.06-fold (95% CI, 8.08 to 21.11) increased risk for breakthrough infection with the Delta variant compared to those previously infected, when the first event (infection or vaccination) occurred during January and February of 2021. The increased risk was significant (P<0.001) for symptomatic disease as well. When allowing the infection to occur at any time before vaccination (from March 2020 to February 2021), evidence of waning natural immunity was demonstrated, though SARS-CoV-2 naive vaccinees had a 5.96-fold (95% CI, 4.85 to 7.33) increased risk for breakthrough infection and a 7.13-fold (95% CI, 5.51 to 9.21) increased risk for symptomatic disease. SARS-CoV-2-naive vaccinees were also at a greater risk for COVID-19-related-hospitalizations compared to those that were previously infected. Conclusions: This study demonstrated that natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity. Individuals who were both previously infected with SARS-CoV-2 and given a single dose of the vaccine gained additional protection against the Delta variant.
It’s interesting but there is also a study published recently that showed that vaccinated individuals had better immunity than previously infected individuals. I think it all lightly boils down to when you do the study in terms of how long ago you had the infection and then your sample size.

I suspect if you studied people three months out from infection and compare them to vaccinating people three months out from vaccination, the immunity conferred by natural infection would probably theoretically be better than the immunity created by the vaccine, but I wonder if you study that with people that were infected a year ago versus people that were vaccinated three or four months ago if the reverse would be true. And that may be why you get different data from different studies.

What is true in both studies and and in all studies so far is that the immunity from previous infection and from vaccination eventually wears off. Here’s where I think people that were infected versus Vaccinated will probably have an advantage because there’s more than one form of immunity in the body and I think that’s why a lot of us have never really gotten sick from Covid because Covid is a coronavirus and a lot of our immune systems have seen that before. Of course there’s a genetic predisposition for those that get sicker than others and so on and so forth but I do think there’s some conferred immunity from previous different types of coronavirus infections that some of us have more than a others.

All interesting speculation but I’ll keep taking my vaccine booster every 6 to 7 months to be safe.
 
Last edited:
  • Like
Reactions: SORT14
Meanwhile, in the United States, well over 95% of the deaths from the Covid Delta variant in the three hospital systems I have data for have been in unvaccinated patients.
 
  • Like
Reactions: jfegaly and SORT14
Hard to imagine natural immunity being less durable than vaccination. This doesn't really impact the issue, if you feel like you need the vax get it, if you don't don't, but either way take care of yourselves or all of this is one giant virtue signaling fest, like almost everything else is now.
I will trust my body to recognize it faster next time plus there will be no delay in taking invermectin next time. That trash vaccine won't be going into my body.
 
I will trust my body to recognize it faster next time plus there will be no delay in taking invermectin next time. That trash vaccine won't be going into my body.
Agree on your body recognizing it better, I won't be putting that crap in me either though, eat more fruits and veggies and get your immune system tuned. Get your bifido ripping.
 
  • Like
Reactions: Gator Fever
Agree on your body recognizing it better, I won't be putting that crap in me either though, eat more fruits and veggies and get your immune system tuned. Get your bifido ripping.
🙄😌🙄
 
Me and my better half continue to be both Fung Flu & Vaccine FREE....
We only wear a mask when it's required and when we need the service provided.
=====

Florida's AD Stricklin announced that they will not require a vaccine or a negative test to attend ANY events on campus, classes or games. They would have, but they were over-ruled by someone that actually follows the science. (thanks yet again to Republican Governor Ron DeSantis)

>>> Of those that have died since they began using the vaccines, over 65% of those now dead were fully vaccinated.

Ron has also recently ordered the availability of the ivermectin antibodies to be made more readily available in Florida to fight the Communist Red Chinese Wuhan Bio-warfare Lab's (intentionally released imo) Kung Flu.

==========

About Ivermectin:

Ivermectin, a US Food and Drug Administration-approved anti-parasitic agent, was found to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in vitro.


A randomized, double-blind, placebo-controlled trial was conducted to determine the rapidity of viral clearance and safety of ivermectin among adult SARS-CoV-2 patients. The trial included 72 hospitalized patients in Dhaka, Bangladesh, who were assigned to one of three groups: oral ivermectin alone (12 mg once daily for 5 days), oral ivermectin in combination with doxycycline (12 mg ivermectin single dose and 200 mg doxycycline on day 1, followed by 100 mg every 12 h for the next 4 days), and a placebo control group. Clinical symptoms of fever, cough, and sore throat were comparable among the three groups. Virological clearance was earlier in the 5-day ivermectin treatment arm when compared to the placebo group (9.7 days vs 12.7 days; p = 0.02), but this was not the case for the ivermectin + doxycycline arm (11.5 days; p = 0.27). There were no severe adverse drug events recorded in the study. A 5-day course of ivermectin was found to be safe and effective in treating adult patients with mild COVID-19. Larger trials will be needed to confirm these preliminary findings.
 
  • Like
Reactions: gatordad3
Me and my better half continue to be both Fung Flu & Vaccine FREE....
We only wear a mask when it's required and when we need the service provided.
=====

Florida's AD Stricklin announced that they will not require a vaccine or a negative test to attend ANY events on campus, classes or games. They would have, but they were over-ruled by someone that actually follows the science. (thanks yet again to Republican Governor Ron DeSantis)

>>> Of those that have died since they began using the vaccines, over 65% of those now dead were fully vaccinated.

Ron has also recently ordered the availability of the ivermectin antibodies to be made more readily available in Florida to fight the Communist Red Chinese Wuhan Bio-warfare Lab's (intentionally released imo) Kung Flu.

==========

About Ivermectin:

Ivermectin, a US Food and Drug Administration-approved anti-parasitic agent, was found to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in vitro.

A randomized, double-blind, placebo-controlled trial
was conducted to determine the rapidity of viral clearance and safety of ivermectin among adult SARS-CoV-2 patients. The trial included 72 hospitalized patients in Dhaka, Bangladesh, who were assigned to one of three groups: oral ivermectin alone (12 mg once daily for 5 days), oral ivermectin in combination with doxycycline (12 mg ivermectin single dose and 200 mg doxycycline on day 1, followed by 100 mg every 12 h for the next 4 days), and a placebo control group. Clinical symptoms of fever, cough, and sore throat were comparable among the three groups. Virological clearance was earlier in the 5-day ivermectin treatment arm when compared to the placebo group (9.7 days vs 12.7 days; p = 0.02), but this was not the case for the ivermectin + doxycycline arm (11.5 days; p = 0.27). There were no severe adverse drug events recorded in the study. A 5-day course of ivermectin was found to be safe and effective in treating adult patients with mild COVID-19. Larger trials will be needed to confirm these preliminary findings.
Eh
You shot all your credibility a long time ago.
 
Eh
You shot all your credibility a long time ago.
So, Clown doc-tor wants to claim that I have no credibility.
Perfect, coming from this hypocritic oath oaf, that's actually a solid compliment.

The data provided didn't come from me or my lab, so my cred (good or bad) doesn't even come into play. This brings up why the blow-hard doc-tor would leap in with his always negative BS drivel..... (those with an IQ over 98 will already know why)

PS --- You've never answered me about if your MALPRACTICE INSURANCE is all paid up or not. That's probably the most important thing that your patients need to know.
 
I’ll be the first one to use ivermectin when there’s a reputable study that shows that it helps. The first American studies should be published at the end of this year.
 
Me and my better half continue to be both Fung Flu & Vaccine FREE....
We only wear a mask when it's required and when we need the service provided.
=====

Florida's AD Stricklin announced that they will not require a vaccine or a negative test to attend ANY events on campus, classes or games. They would have, but they were over-ruled by someone that actually follows the science. (thanks yet again to Republican Governor Ron DeSantis)

>>> Of those that have died since they began using the vaccines, over 65% of those now dead were fully vaccinated.

Ron has also recently ordered the availability of the ivermectin antibodies to be made more readily available in Florida to fight the Communist Red Chinese Wuhan Bio-warfare Lab's (intentionally released imo) Kung Flu.

==========

About Ivermectin:

Ivermectin, a US Food and Drug Administration-approved anti-parasitic agent, was found to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in vitro.

A randomized, double-blind, placebo-controlled trial
was conducted to determine the rapidity of viral clearance and safety of ivermectin among adult SARS-CoV-2 patients. The trial included 72 hospitalized patients in Dhaka, Bangladesh, who were assigned to one of three groups: oral ivermectin alone (12 mg once daily for 5 days), oral ivermectin in combination with doxycycline (12 mg ivermectin single dose and 200 mg doxycycline on day 1, followed by 100 mg every 12 h for the next 4 days), and a placebo control group. Clinical symptoms of fever, cough, and sore throat were comparable among the three groups. Virological clearance was earlier in the 5-day ivermectin treatment arm when compared to the placebo group (9.7 days vs 12.7 days; p = 0.02), but this was not the case for the ivermectin + doxycycline arm (11.5 days; p = 0.27). There were no severe adverse drug events recorded in the study. A 5-day course of ivermectin was found to be safe and effective in treating adult patients with mild COVID-19. Larger trials will be needed to confirm these preliminary findings.


Worth repeating
c0ea5092-da7f-479d-b0ed-7e7f56283daa-png.34793
 
ADVERTISEMENT
ADVERTISEMENT